The Red Queen is Alice’s daughter
In The Final Chapter the Red Queen and the young Alicia Marcus are played by Ever Anderson, the daughter of Milla Jovovich and Paul W. S. Anderson.
Source: English Wikipedia, “Resident Evil: The Final Chapter”
2016
The Red Queen sends Alice back to the Hive under Raccoon City, where Umbrella keeps an airborne antivirus. The last humans have 48 hours. Paul W. S. Anderson’s final film in the series opened in Japan in December 2016.

In The Final Chapter the Red Queen and the young Alicia Marcus are played by Ever Anderson, the daughter of Milla Jovovich and Paul W. S. Anderson.
Source: English Wikipedia, “Resident Evil: The Final Chapter”
The Final Chapter earned over $312 million worldwide on a $40 million budget. Mainland China was its largest market outside the US, at $160 million.
Source: English Wikipedia, “Resident Evil: The Final Chapter”
The Final Chapter was set to start shooting in South Africa in August 2014 and was delayed a year because of Jovovich’s pregnancy. Photography began on 18 September 2015.
Source: English Wikipedia, “Resident Evil: The Final Chapter”

South Africa
Cape Town
On screen
A location of The Final Chapter
Principal photography of The Final Chapter began on 18 September 2015 in South Africa; the film’s Wikipedia article names Cape Town and Hartbeespoort Dam. The photograph shows Camps Bay in Cape Town.
Der Berzerker / CC BY-SA 2.0 (Wikimedia Commons)